Berberine has been studied for its potential to help regulate blood sugar levels. In one study, berberine was found to improve glycemic control in patients with type 2 diabetes by reducing fasting blood glucose, postprandial blood glucose, and hemoglobin A1c (HbA1c). It was also found to reduce insulin resistance, improve glucose tolerance, and reduce triglyceride levels. Other studies have also shown that berberine may help to reduce blood sugar levels in people with type 2 diabetes.